PGA and its copolymer - Names and Identifiers
PGA and its copolymer - Physico-chemical Properties
| Physical and Chemical Properties | Chemical properties Tensile strength is 57MPa, bending strength is 150MPa ± 50MPa. |
| Use | Uses the PGA fibers are woven into spongy or gauze blocks for surgical applications, such as covering the organs or liver used for bleeding, repairing and restoring in vivo, and making bone nails, bone plates and rods; PGA fibers can also be woven into drug coatings and various repair of burn patients. |
PGA and its copolymer - Production method
P> polyglycolic acid can be obtained by polymerizing glycolic acid. the degree of polymerization of this directly obtained polyglycolic acid is very low, generally several to tens. after glycolic ester is prepared by dehydration with industrial ethanol, polyglycolic acid with high degree of polymerization can be obtained by ring-opening polymerization with glycolic acid. in the presence of Sb2O2, glycolic acid is heated at 180 ℃ and pressurized for 5Pa, in the presence of Sn and C12H25OH, glycolide polymerizes polyglycolic acid with high polymerization degree.
In the process of preparing polyglycolic acid, the formation of glycolide is an effective way. Glycolide is a dimer for the dehydration of glycolic acid. During the ring-opening polymerization of glycolide, a small part of the ethanol ester is reacted head-to-head to generate anhydride or polyglycolic acid. The relative molecular mass is 10000, and the relative molecular mass is more than 100000. When the processing is difficult, the melt viscosity is 400-27000 mPa.s at 245 ℃, and the glass transition temperature is 36 ℃.
Polyglycolic acid suture: A large amount of polyglycolic acid is used for the preparation of absorbable surgical sutures. It is formed by mixing the synthesized PGA polymer with dyeing material, heating and melting to make fibers and weaving.
Last Update：2024-04-10 22:29:15